Schedules of Controlled Substances: Placement of 4F-MDMB-BUTICA, ADB-4en-PINACA, 5F-EDMB-PICA, and MMB-FUBICA in Schedule I
Built by the Tribune's code from the Federal Register. No AI wrote this page. Published in the Federal Register May 1, 2026. Document 2026-08517. Updated Nov. 11, 2026.
- What it does
With the issuance of this final rule, the Drug Enforcement Administration places methyl 2-[[1-(4-fluorobutyl)indole-3- carbonyl]amino]-3,3-dimethyl-butanoate (other names: 4F-MDMB-BUTICA; 4F-MDMB-BICA), N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(pent-4-en-1- yl)-1H-indazole-3-carboxamide (other name: ADB-4en-PINACA), ethyl 2- [[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl-butanoate (other names: 5F-EDMB-PICA; 5F-EDMB-2201), and methyl 2-(1-(4- fluorobenzyl)-1H-indole-3-carboxamido)-3-methyl butanoate (other name: MMB-FUBICA), including their salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible, in schedule I of the Controlled Substances Act. This action imposes regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis with, or possess) or propose to handle 4F-MDMB-BUTICA, ADB- 4en-PINACA, 5F-EDMB-PICA, or MMB-FUBICA.
The Drug Enforcement Administration's summary, as published in the Federal Register.
- What changed in the regulation
1 part of Title 21 of the Code of Federal Regulations:
Wording on eCFR: the day before it took effect and from the day it took effect (first part listed).
- Compared with
The Drug Enforcement Administration has published 26 final rules in 2026 so far, compared with 17 in all of 2025.
Counted by the Tribune from Federal Register records since Jan. 1, 2025.
- What happens next and when
Effective date: May 1, 2026.
The agency's dates, word for word.
The record as published
| Document number | 2026-08517 |
|---|---|
| Action | Final rule. |
| Agencies | Justice Department; Drug Enforcement Administration |
| Published | May 1, 2026 |
| Effective date | May 1, 2026 |
| Docket | DEA-2025-0918 |
Source: the Federal Register (public domain). The document in the Federal Register