Significant New Use Rules on Certain Chemical Substances (25-3.5e)

What it does

EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.

The Environmental Protection Agency's summary, as published in the Federal Register.

What changed in the regulation

1 part of Title 40 of the Code of Federal Regulations:

40 CFR 721

Compared with

The Environmental Protection Agency has published 243 final rules in 2026 so far, compared with 263 in all of 2025.

Counted by the Tribune from Federal Register records since Jan. 1, 2025.

Before this

27 earlier Federal Register documents under regulation identifier 2070-AB27 since Jan. 1, 2025.

• Nov. 2, 2026 Proposed rule. Significant New Use Rules on Certain Chemical Substances (26-7)
• Oct. 15, 2026 Final rule; correction. Significant New Use Rules on Certain Chemical Substances (24-5.5e); Correction
• Oct. 15, 2026 Final rule. Significant New Use Rules on Certain Chemical Substances (26-1)
• Aug. 26, 2026 Final rule. Significant New Use Rules on Certain Chemical Substances (24-5.5e)
• July 30, 2026 Proposed rule. Significant New Use Rules on Certain Chemical Substances (26-4)
• July 24, 2026 Final rule. Significant New Use Rule on a Certain Chemical Substance; Multi-Walled Carbon Nanotubes
• July 23, 2026 Proposed rule. Significant New Use Rules on Certain Chemical Substances (26-3)
• June 10, 2026 Proposed rule. Significant New Use Rules on Certain Chemical Substances (26-1)

What happens next and when

This rule is effective on January 4, 2027. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EST) on November 19, 2026.

The agency's dates, word for word.

Check it yourself

• The document in the Federal Register
• Docket EPA-HQ-OPPT-2025-2169 on Regulations.gov
• Title 40 on eCFR

The record as published

Source: the Federal Register (public domain). The document in the Federal Register