Drug Enforcement Administration: federal rules
The Drug Enforcement Administration published 25 final rules in 2026 so far and 17 in 2025, counted by the Tribune from the Federal Register.
Built by the Tribune's code from the Federal Register. No AI wrote this page. Updated Nov. 2, 2026.
Final rules 42
- Nov. 2, 2026Conforming Amendment Regarding the Criminal Law Technical Amendments Act of 2002
Final rule · Drug Enforcement Administration · 21 CFR part 1301
- Oct. 30, 2026Schedules of Controlled Substances: Placement of Centanafadine in Schedule III
Final rule · Drug Enforcement Administration · 21 CFR part 1308
- Oct. 9, 2026Schedules of Controlled Substances; Removal of Exemption Status for Inactive Butalbital Products
Final rule · Drug Enforcement Administration · 21 CFR part 1308
- Sept. 21, 2026Schedules of Controlled Substances: Placement of Diphenidine in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 27, 2026Schedules of Controlled Substances: Temporary Placement of 5,6-Dichloro Brorphine, 5,6-Dichloro Desmethylchlorphine, N-Propionitrile Chlorphine, and Spirochlorphine in Schedule I of the Controlled Substances Act
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 27, 2026Schedules of Controlled Substances: Placement of Cipepofol in Schedule IV
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 26, 2026Schedules of Controlled Substances: Temporary Placement of Mitragynine Pseudoindoxyl, MGM-15, and MGM-16 in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 12, 2026Schedules of Controlled Substances: Temporary Placement of O-Desmethyltramadol in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- June 24, 2026Schedules of Controlled Substances: Temporary Placement of O-Desmethyltramadol in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- June 9, 2026Implementation of the Substance Use-Disorder Prevention That Promotes Opioid Recovery and Treatment for Patients and Communities Act of 2018: Dispensing and Administering Controlled Substances for Medication-Assisted Treatment
Final rule · Drug Enforcement Administration · 21 CFR parts 1300, 1301, 1306 · Opens the Federal Register
- May 22, 2026Schedules of Controlled Substances: Temporary Placement of 2-Fluorodeschloroketamine in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- May 13, 2026Schedules of Controlled Substances: Placement of CUMYL-PEGACLONE in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- May 4, 2026Specific Listing for Hexahydrocannabinol, A Currently Controlled Schedule I Substance
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- May 1, 2026Schedules of Controlled Substances: Placement of 4F-MDMB-BUTICA, ADB-4en-PINACA, 5F-EDMB-PICA, and MMB-FUBICA in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- April 28, 2026Schedules of Controlled Substances: Rescheduling of Food and Drug Administration Approved Products Containing Marijuana From Schedule I to Schedule III; Corresponding Change to Permit Requirements
Final rule · Drug Enforcement Administration · 21 CFR parts 1300, 1301, 1308 and 1 more · Opens the Federal Register
- April 24, 2026Schedules of Controlled Substances: Placement of MDMB-4en-PINACA in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- April 3, 2026Designation of P2P Methyl Glycidic Acid as a List I Chemical
Final rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- March 23, 2026Schedules of Controlled Substances: Placement of 3-Methoxyphencyclidine (1-(1-(3-Methoxyphenyl)cyclohexyl)piperidine) in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- March 16, 2026Schedules of Controlled Substances: Temporary Placement of Bromazolam in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- March 10, 2026Designation of Propionyl Chloride as a List I Chemical
Final rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- March 2, 2026Schedules of Controlled Substances: Placement of Clonazolam, Diclazepam, Etizolam, Flualprazolam, and Flubromazolam in Schedule I of the Controlled Substances Act
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Feb. 5, 2026Registering Emergency Medical Services Agencies Under the Protecting Patient Access to Emergency Medications Act of 2017
Final rule · Drug Enforcement Administration · 21 CFR parts 1300, 1301, 1304 and 2 more · Opens the Federal Register
- Jan. 20, 2026Definition of “Cannabimimetic Agents” and Assignment of an Administration Controlled Substances Code Number for All “Cannabimimetic Agents”
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Jan. 15, 2026Schedules of Controlled Substances: Placement of 4-Fluoroamphetamine in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Jan. 12, 2026Schedules of Controlled Substances: Placement of N-Pyrrolidino Metonitazene and N-Pyrrolidino Protonitazene in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 31, 2025Fourth Temporary Extension of COVID-19 Telemedicine Flexibilities for Prescription of Controlled Medications
Final rule · Drug Enforcement Administration · 2 parts · Opens the Federal Register
- Dec. 23, 2025Schedules of Controlled Substances: Placement of N-Desethyl Isotonitazene and N-Piperidinyl Etonitazene in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 16, 2025Schedules of Controlled Substances: Extension of Temporary Placement of 4F-MDMB-BUTICA, ADB-4en-PINACA, 5F-EDMB-PICA, and MMB-FUBICA in Schedule I of the Controlled Substances Act
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 11, 2025Schedules of Controlled Substances: Extension of Temporary Placement of CUMYL-PEGACLONE in Schedule I of the Controlled Substances Act
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 11, 2025Schedules of Controlled Substances: Extension of Temporary Placement of MDMB-4en-PINACA in Schedule I of the Controlled Substances Act
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Nov. 17, 2025Schedules of Controlled Substances: Placement of 4-Chloromethcathinone in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Oct. 15, 2025Schedules of Controlled Substances: Temporary Placement of Ethyleneoxynitazene, Methylenedioxynitazene, 5-Methyl Etodesnitazene, N-Desethyl Etonitazene, N-Desethyl Protonitazene, N,N-Dimethylamino Etonitazene, and N-Pyrrolidino Isotonitazene in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Oct. 2, 2025Controlled Substances Ordering System (CSOS) Modernization
Final rule · Drug Enforcement Administration · 21 CFR part 1311 · Opens the Federal Register
- Oct. 2, 2025Specific Listing for 1-boc-4-piperidone, a Currently Controlled List I Chemical
Final rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- Sept. 18, 2025Schedules of Controlled Substances: Placement of Seven Specific Fentanyl-Related Substances in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 15, 2025Schedules of Controlled Substances: Temporary Placement of N-pyrrolidino metonitazene and N-pyrrolidino protonitazene in Schedule I
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 8, 2025Specific Listing for Dipentylone, a Currently Controlled Schedule I Substance
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- July 25, 2025Schedules of Controlled Substances: Extension of Temporary Placement of Clonazolam, Diclazepam, Etizolam, Flualprazolam, and Flubromazolam in Schedule I of the Controlled Substances Act
Final rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- March 24, 2025Expansion of Buprenorphine Treatment via Telemedicine Encounter and Continuity of Care via Telemedicine for Veterans Affairs Patients
Final rule · Drug Enforcement Administration · 2 parts · Opens the Federal Register
- Feb. 19, 2025Expansion of Buprenorphine Treatment via Telemedicine Encounter and Continuity of Care via Telemedicine for Veterans Affairs Patients
Final rule · Drug Enforcement Administration · 2 parts · Opens the Federal Register
- Jan. 17, 2025Continuity of Care via Telemedicine for Veterans Affairs Patients
Final rule · Drug Enforcement Administration · 2 parts · Opens the Federal Register
- Jan. 17, 2025Expansion of Buprenorphine Treatment via Telemedicine Encounter
Final rule · Drug Enforcement Administration · 2 parts · Opens the Federal Register
Proposed rules 28
- Oct. 14, 2026Schedules of Controlled Substances: Temporary Placement of MGM-15 and MGM-16 in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308
- Oct. 14, 2026
- Oct. 1, 2026Extension of Reexportation Period.
Proposed rule · Drug Enforcement Administration · 21 CFR part 1312 · Opens the Federal Register
- Sept. 23, 2026Schedules of Controlled Substances: Placement of 4-Hydroxy-N,N-Diisopropyltryptamine (4-OH-DiPT), 5-Methoxy-alpha-Methyltryptamine (5-MeO-AMT), 5-Methoxy-N-Methyl-N-Isopropyltryptamine (5-MeO-MiPT), 5-Methoxy-N,N-Diethyltryptamine (5-MeO-DET), and N,N-Diisopropyltryptamine (DiPT) Into Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 11, 2026Schedules of Controlled Substances: Rescheduling of Suvorexant, Lemborexant, and Daridorexant From Schedule IV Into Schedule V
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Aug. 3, 2026Amendment to 3,4-MDP-2-P Methyl Glycidic Acid, a List I Chemical
Proposed rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- July 9, 2026Designation of Phenethyl Halides as List I Chemicals
Proposed rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- July 8, 2026Schedules of Controlled Substances: Placement of Tianeptine in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- July 6, 2026Schedules of Controlled Substance: Temporary Placement of 7-Hydroxymitragynine Above a Specified Threshold in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- July 6, 2026Schedules of Controlled Substances: Temporary Placement of Mitragynine Pseudoindoxyl, MGM-15, and MGM-16 in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- July 1, 2026Schedules of Controlled Substances: Temporary Placement of 5,6- Dichloro Brorphine, 5,6-Dichloro Desmethylchlorphine, N-Propionitrile Chlorphine, and Spirochlorphine in Schedule I of the Controlled Substances Act
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- May 26, 2026Schedules of Controlled Substances; Removal of Exemption Status for Inactive Butalbital Products
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- May 26, 2026Schedules of Controlled Substances: Placement of Diphenidine in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- May 20, 2026Revision of Applications for Manufacturing and Procurement Quotas
Proposed rule · Drug Enforcement Administration · 21 CFR parts 1303, 1315 · Opens the Federal Register
- April 28, 2026Schedules of Controlled Substances: Rescheduling of Marijuana
Proposed rule · Drug Enforcement Administration · 21 CFR part 1301 · Opens the Federal Register
- Jan. 20, 2026Schedules of Controlled Substances: Temporary Placement of 2-Fluorodeschloroketamine in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 16, 2025Schedules of Controlled Substances: Placement of 4F-MDMB-BUTICA, ADB-4en-PINACA, 5F-EDMB-PICA, and MMB-FUBICA in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 15, 2025Schedules of Controlled Substances: Temporary Placement of Bromazolam in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Dec. 11, 2025Schedules of Controlled Substances: Placement of CUMYL-PEGACLONE in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Oct. 2, 2025Schedules of Controlled Substances: Placement of MDMB-4en-PINACA in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Oct. 2, 2025Designation of P2P Methyl Glycidic Acid as a List I Chemical
Proposed rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- July 25, 2025Schedules of Controlled Substances: Placement of Clonazolam, Diclazepam, Etizolam, Flualprazolam, and Flubromazolam in Schedule I of the Controlled Substances Act
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- June 26, 2025Schedules of Controlled Substances: Temporary Placement of Seven Benzimidazole-Opioids in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- June 10, 2025Schedules of Controlled Substances: Placement of Three Specific Fentanyl-Related Substances in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- June 10, 2025Schedules of Controlled Substances: Placement of 3-Methoxyphencyclidine (1-[1-(3-methoxyphenyl)cyclohexyl]piperidine) in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- June 3, 2025Designation of Propionyl Chloride as a List I Chemical
Proposed rule · Drug Enforcement Administration · 21 CFR part 1310 · Opens the Federal Register
- June 3, 2025Schedules of Controlled Substances: Placement of 4-Fluoroamphetamine in Schedule I
Proposed rule · Drug Enforcement Administration · 21 CFR part 1308 · Opens the Federal Register
- Jan. 17, 2025Special Registrations for Telemedicine and Limited State Telemedicine Registrations
Proposed rule · Drug Enforcement Administration · 21 CFR parts 1300, 1301, 1304 and 1 more · Opens the Federal Register